Genome Guardian

Dive into a microscopic alien world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive 70 different microbes across 8 game modes, each with multiple ascension levels ("depths").



Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!

• Bomb + Shotgun combines explosives with spread to create Blast Shotgun!
• Bomb + Bomb doubles down on explosive power to make Bazooka!
• Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!

• 49 Turrets with unique strengths and functions
• 96 Perks to mix and match that drastically change how you play
• 72 Turret & Weapon Mods that can turn shots into sticky mines or bouncing fireballs
• 32 Mutations that alter the challenges you face each run

• 20-minute Runs that can be continued in Endless Mode
• 60 Bassy Electronic Tunes that adapt to the current mood and intensity
• 100 Steam Achievements
• 49 Cosmetics including spider legs, tank tread and a swarm of drones
• Accessibility Settings for colourblindness and motion sickness
• Cloud Save
• Plays great on Steam Deck! (official Steam Deck Compatibility Review pending)

Genome Guardian is a product of passion - a culmination of everything I love about roguelite shooters, and a novel 'weapon-combining' feature that I've wanted to realize since I was a teenager. Your support will mean content updates and allow me to make more games in the future.